SAMe 400mg Capsules 30



S-adenosyl-L-methionine (SAMe) is a compound found naturally in the body. SAMe helps produce and regulate hormones and maintain cell membranes.

Research on SAMe use for specific conditions shows:

  • Depression. While research has shown that SAMe has a positive effect in treating depression, most studies weren’t well designed and included a small number of people.
  • Liver disease. More studies are needed to determine whether SAMe is beneficial for people who have liver disease.
  • Osteoarthritis. Many studies comparing the use of SAMe with nonsteroidal anti-inflammatory drugs showed that each provided similar pain relief and improvement in joint function, but SAMe produced fewer side effects. A smaller number of studies haven’t shown the same results.


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